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Features of nephrotic syndrome

Medicine · exam-style practice question with explanation

Which combination defines nephrotic syndrome?

  1. A. Haematuria, hypertension and oliguria
  2. B. Heavy proteinuria, hypoalbuminaemia and oedema
  3. C. Pyuria, fever and loin pain
  4. D. Glycosuria, polyuria and polydipsia
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Answer: B. Heavy proteinuria, hypoalbuminaemia and oedema

Nephrotic syndrome is heavy proteinuria (over 3.5 g a day in adults), low serum albumin and oedema, usually with high cholesterol. Haematuria, hypertension and oliguria describe nephritic syndrome instead.

Key point: Nephrotic: protein out, albumin down, oedema. Nephritic: blood, hypertension, oliguria.

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