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Nerve injured in a mid-shaft humerus fracture

Anatomy · exam-style practice question with explanation

After a fracture of the shaft of the humerus, a patient cannot extend the wrist (wrist drop). Which nerve is injured?

  1. A. Median nerve
  2. B. Ulnar nerve
  3. C. Radial nerve
  4. D. Axillary nerve
Show the answer and explanation

Answer: C. Radial nerve

The radial nerve runs in the spiral (radial) groove of the humerus, so it is at risk in mid-shaft fractures. Injury causes wrist drop, from weakness of the wrist and finger extensors, and sensory loss over the back of the hand near the thumb.

Key point: Mid-shaft humerus fracture: radial nerve, wrist drop.

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